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Mitochondria: the headquarters in ischemia-induced ...

    https://www.ncbi.nlm.nih.gov/pubmed/21521170
    Jun 01, 2011 · Mitochondria: the headquarters in ischemia-induced neuronal death. Jordan J(1), de Groot PW, Galindo MF. Author information: (1)Grupo de Neurofarmacologia, Dpto Ciencias Médicas, Facultad de Medicina, Universidad de Castilla-La Mancha, and Unidad de Neuropsicofarmacología Translacional, Complejo Hospitalario Universitario de Albacete, C ...Cited by: 21

Mitochondria: the Headquarters in Ischemia-Induced ...

    https://www.eurekaselect.com/88240/article
    In this review we summarize and discuss the role of mitochondrial participation in ischemia-induced neuronal death. Mitochondria are regarded as the main link between cellular stress signals and the execution of programmed death of nerve cells.Cited by: 21

Mitochondrial Fusion and Fission in Neuronal Death Induced ...

    https://pubmed.ncbi.nlm.nih.gov/33156817/
    Cerebral ischemia-reperfusion (I/R) injury can disrupt the balance of mitochondrial fusion and fission through regulating the expression and post-translation modification of fusion- and fission-related proteins, thereby destroying homeostasis of the intracellular environment and causing neuronal death.Cited by: 1

Molecular mechanisms of cerebral ischemia-induced neuronal ...

    https://pubmed.ncbi.nlm.nih.gov/12455747/
    The ischemia-induced neuronal death is an active process (energy dependent) and is the result of activation of cascades of detrimental biochemical events that include perturbion of calcium homeostasis leading to increased excitotoxicity, malfunction of endoplasmic reticulum and mitochondria, elevation of oxidative stress causing DNA damage ...Cited by: 235

Diverse roles of mitochondria in ischemic stroke

    https://pubmed.ncbi.nlm.nih.gov/29549824/
    Diverse roles of mitochondria in ischemic stroke Redox Biol. 2018 Jun;16:263-275. doi: 10.1016/j.redox.2018.03.002 . ... A better understanding of the roles of mitochondria in ischemia-related neuronal death and protection may provide a rationale for the development of innovative therapeutic regimens for ischemic stroke and other stroke ...Cited by: 144

Mitochondrial mechanisms of neuronal rescue by F-68, a ...

    https://pubmed.ncbi.nlm.nih.gov/28433663/
    Global brain ischemia can lead to widespread neuronal death and poor neurologic outcomes in patients. Despite detailed understanding of the cellular and molecular mechanisms mediating neuronal death following focal and global brain hypoxia-ischemia, treatments to reduce ischemia-induced brain injury remain elusive.Cited by: 8

Ischemic delayed neuronal death. A mitochondrial hypothesis.

    https://www.ncbi.nlm.nih.gov/pubmed/7631357
    1. Stroke. 1995 Aug;26 (8):1478-89. Ischemic delayed neuronal death. A mitochondrial hypothesis. Abe K (1), Aoki M, Kawagoe J, Yoshida T, Hattori A, Kogure K, Itoyama Y. (1)Department of Neurology, Tohoku University School of Medicine, Sendai, Japan. BACKGROUND: A brief period of global brain ischemia causes cell death in hippocampal CA1 ...Cited by: 400

joaquin Jordan University of Castilla-La ... - Academia.edu

    https://uclm.academia.edu/joaquinJordan
    Mitochondria: the Headquarters in Ischemia-Induced Neuronal Death more by joaquin Jordan Due to a lack of efficient treatments, searching for novel therapies against acute ischemic stroke represents one of the main fields in neuropharmacology.

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